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10.1038/nsmb.3324 http://scihub22266oqcxt.onion/10.1038/nsmb.3324 C5497498!5497498 !27922611     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27922611 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27922611 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Struct+Mol+Biol 2016 ; 23 (12 ): 1045-1052 Nephropedia Template TP {{tp|p=27922611 |t=2016. Genetic and epigenomic mechanisms of mammalian circadian transcription |pdf=|usr=}}{{27922611 }} gab.com Text Genetic and epigenomic mechanisms of mammalian circadian transcription JO: Nat Struct Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=27922611 #FOAvip The mammalian molecular clock comprises a complex network of transcriptional programs that integrates environmental signals with physiological pathways in a tissue-specific manner. Emerging technologies are extending knowledge of basic clock features by uncovering their underlying molecular mechanisms, thus setting the stage for a 'systems' view of the molecular clock. Here we discuss how recent data from genome-wide genetic and epigenetic studies have informed the understanding of clock function. In addition to its importance in human physiology and disease, the clock mechanism provides an ideal model to assess general principles of dynamic transcription regulation in vivo. Twit Text FOAVip Genetic and epigenomic mechanisms of mammalian circadian transcription ????Nat Struct Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=27922611 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27922611 #FOAvip English Wikipedia <ref>{{Cite pmid|27922611 }}</ref> Genetic and epigenomic mechanisms of mammalian circadian transcription #MMPMID27922611 Papazyan R ; Zhang Y ; Lazar MA Nat Struct Mol Biol 2016[Dec]; 23 (12 ): 1045-1052 PMID27922611 show ga The mammalian molecular clock comprises a complex network of transcriptional programs that integrates environmental signals with physiological pathways in a tissue-specific manner. Emerging technologies are extending knowledge of basic clock features by uncovering their underlying molecular mechanisms, thus setting the stage for a 'systems' view of the molecular clock. Here we discuss how recent data from genome-wide genetic and epigenetic studies have informed the understanding of clock function. In addition to its importance in human physiology and disease, the clock mechanism provides an ideal model to assess general principles of dynamic transcription regulation in vivo. |*Circadian Clocks [MESH] |*Transcriptional Activation [MESH] |Animals [MESH] |Circadian Rhythm [MESH] |DNA Methylation [MESH] |Epigenomics/methods [MESH] |Gene Expression Regulation [MESH] |Histones/genetics/metabolism [MESH] |Humans [MESH] |Protein Interaction Maps [MESH] |Signal Transduction [MESH] |Transcription Factors/genetics/metabolism [MESH]Genetic and epigenomic mechanisms of mammalian circadian transcription(epmc).pdf DeepDyve Pubget Overpricing