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10.1136/jclinpath-2016-203650 http://scihub22266oqcxt.onion/10.1136/jclinpath-2016-203650 C4914571!4914571 !26941181     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26941181 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Clin+Pathol 2016 ; 69 (6 ): 484-9 Nephropedia Template TP {{tp|p=26941181 |t=2016. Gene of the month: SMARCB1 |pdf=|usr=}}{{26941181 }} gab.com Text Gene of the month: SMARCB1 JO: J Clin Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26941181 #FOAvip SMARCB1 is the core subunit of the SWI/sucrose non-fermenting ATP-dependent chromatin remodelling complex located on the long arm of chromosome 22 (22q11.2). Since discovering genetic alterations of the SMARCB1 gene in malignant rhabdoid tumours, the family of tumours harbouring loss of SMARCB1 expression has been steadily expanding. In this review, we give a general overview of SMARCB1, its role in various cancers including germline mutations, association with genetic syndromes and role in future targeted therapies. Twit Text FOAVip Gene of the month: SMARCB1 ????J Clin Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26941181 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26941181 #FOAvip English Wikipedia <ref>{{Cite pmid|26941181 }}</ref> Gene of the month: SMARCB1 #MMPMID26941181 Kalimuthu SN ; Chetty R J Clin Pathol 2016[Jun]; 69 (6 ): 484-9 PMID26941181 show ga SMARCB1 is the core subunit of the SWI/sucrose non-fermenting ATP-dependent chromatin remodelling complex located on the long arm of chromosome 22 (22q11.2). Since discovering genetic alterations of the SMARCB1 gene in malignant rhabdoid tumours, the family of tumours harbouring loss of SMARCB1 expression has been steadily expanding. In this review, we give a general overview of SMARCB1, its role in various cancers including germline mutations, association with genetic syndromes and role in future targeted therapies. |Carcinoma/*genetics [MESH] |Chromatin Assembly and Disassembly [MESH] |Chromosomes, Human, Pair 22/genetics [MESH] |Gene Expression Regulation, Neoplastic [MESH] |Genetic Diseases, Inborn/*genetics [MESH] |Germ-Line Mutation [MESH] |Humans [MESH] |Kidney Neoplasms/*genetics [MESH] |Molecular Targeted Therapy [MESH] |Multiprotein Complexes [MESH] |Rhabdoid Tumor/*genetics [MESH] |SMARCB1 Protein/*genetics/metabolism [MESH] |Sarcoma/*genetics [MESH]Gene of the month: SMARCB1 (epmc).pdf DeepDyve Pubget Overpricing