Clin Sci (Lond)
2016[Jun]; 130
(12
): 1005-16
PMID27154744
show ga
The recent discovery of the G protein-coupled oestrogen receptor (GPER) presents
new challenges and opportunities for understanding the physiology,
pathophysiology and pharmacology of many diseases. This review will focus on the
expression and function of GPER in hypertension, kidney disease, atherosclerosis,
vascular remodelling, heart failure, reproduction, metabolic disorders, cancer,
environmental health and menopause. Furthermore, this review will highlight the
potential of GPER as a therapeutic target.