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2016 ; 7
(2
): 155-66
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Functions of long noncoding RNAs in the nucleus
#MMPMID27105038
Yu B
; Shan G
Nucleus
2016[Apr]; 7
(2
): 155-66
PMID27105038
show ga
Nucleus is the residence and place of work for a plethora of long noncoding RNAs.
Here, we provide a summary of the functions and functional mechanisms of several
relatively well studied examples of nuclear long noncoding RNAs (lncRNAs) in the
nucleus, such as Xist, NEAT1, MALAT1 and TERRA. The recently identified novel
EIciRNA is also highlighted. These nuclear lncRNAs play a variety of roles with
diverse molecular mechanisms in animal cells. We also discuss insights and
concerns about current and future studies of nuclear lnc RNAs.