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10.1016/j.semcdb.2014.05.015 http://scihub22266oqcxt.onion/10.1016/j.semcdb.2014.05.015 C4163095!4163095 !24965208     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24965208 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Semin+Cell+Dev+Biol 2014 ; 34 (ä): 9-14 Nephropedia Template TP {{tp|p=24965208 |t=2014. Functional interactions among microRNAs and long noncoding RNAs |pdf=|usr=}}{{24965208 }} gab.com Text Functional interactions among microRNAs and long noncoding RNAs JO: Semin Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=24965208 #FOAvip In mammals, the vast majority of transcripts expressed are noncoding RNAs, ranging from short RNAs (including microRNAs) to long RNAs spanning up to hundreds of kb. While the actions of microRNAs as destabilizers and repressors of the translation of protein-coding transcripts (mRNAs) have been studied in detail, the influence of microRNAs on long noncoding RNA (lncRNA) function is only now coming into view. Conversely, the influence of lncRNAs upon microRNA function is also rapidly emerging. In some cases, lncRNA stability is reduced through the interaction of specific miRNAs. In other cases, lncRNAs can act as microRNA decoys, with the sequestration of microRNAs favoring expression of repressed target mRNAs. Other lncRNAs derepress gene expression by competing with miRNAs for interaction with shared target mRNAs. Finally, some lncRNAs can produce miRNAs, leading to repression of target mRNAs. These microRNA-lncRNA regulatory paradigms modulate gene expression patterns that drive major cellular processes (such as cell differentiation, proliferation, and cell death) which are central to mammalian physiologic and pathologic processes. We review and summarize the types of microRNA-lncRNA crosstalk identified to-date and discuss their influence on gene expression programs. Twit Text FOAVip Functional interactions among microRNAs and long noncoding RNAs ????Semin Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=24965208 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24965208 #FOAvip English Wikipedia <ref>{{Cite pmid|24965208 }}</ref> Functional interactions among microRNAs and long noncoding RNAs #MMPMID24965208 Yoon JH ; Abdelmohsen K ; Gorospe M Semin Cell Dev Biol 2014[Oct]; 34 (ä): 9-14 PMID24965208 show ga In mammals, the vast majority of transcripts expressed are noncoding RNAs, ranging from short RNAs (including microRNAs) to long RNAs spanning up to hundreds of kb. While the actions of microRNAs as destabilizers and repressors of the translation of protein-coding transcripts (mRNAs) have been studied in detail, the influence of microRNAs on long noncoding RNA (lncRNA) function is only now coming into view. Conversely, the influence of lncRNAs upon microRNA function is also rapidly emerging. In some cases, lncRNA stability is reduced through the interaction of specific miRNAs. In other cases, lncRNAs can act as microRNA decoys, with the sequestration of microRNAs favoring expression of repressed target mRNAs. Other lncRNAs derepress gene expression by competing with miRNAs for interaction with shared target mRNAs. Finally, some lncRNAs can produce miRNAs, leading to repression of target mRNAs. These microRNA-lncRNA regulatory paradigms modulate gene expression patterns that drive major cellular processes (such as cell differentiation, proliferation, and cell death) which are central to mammalian physiologic and pathologic processes. We review and summarize the types of microRNA-lncRNA crosstalk identified to-date and discuss their influence on gene expression programs. |Animals [MESH] |Humans [MESH] |MicroRNAs/*physiology [MESH] |RNA Interference [MESH]Functional interactions among microRNAs and long noncoding RNAs (epmc).pdf DeepDyve Pubget Overpricing