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2020 ; 11
(5
): 857-862
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Functional and cognitive outcomes after COVID-19 delirium
#MMPMID32666303
Mcloughlin BC
; Miles A
; Webb TE
; Knopp P
; Eyres C
; Fabbri A
; Humphries F
; Davis D
Eur Geriatr Med
2020[Oct]; 11
(5
): 857-862
PMID32666303
show ga
PURPOSE: To ascertain delirium prevalence and outcomes in COVID-19. METHODS: We
conducted a point-prevalence study in a cohort of COVID-19 inpatients at
University College Hospital. Delirium was defined by DSM-IV criteria. The primary
outcome was all-cause mortality at 4 weeks; secondary outcomes were physical and
cognitive function. RESULTS: In 71 patients (mean age 61, 75% men), 31 (42%) had
delirium, of which only 12 (39%) had been recognised by the clinical team. At
4 weeks, 20 (28%) had died, 26 (36%) were interviewed by telephone and 21 (30%)
remained as inpatients. Physical function was substantially worse in people after
delirium -?50 out of 166 points (95% CI -?83 to -?17, p?=?0.01). Mean cognitive
scores at follow-up were similar and delirium was not associated with mortality
in this sample. CONCLUSIONS: Our findings indicate that delirium is common, yet
under-recognised. Delirium is associated with functional impairments in the
medium term.