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10.1172/JCI80004 http://scihub22266oqcxt.onion/10.1172/JCI80004 C4588291!4588291!26241053     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26241053.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Clin+Invest 2015 ; 125 (9): 3338-46 Nephropedia Template TP {{tp|p=26241053|t=2015. From mice to humans: developments in cancer immunoediting |pdf=|usr=}}{{26241053}} gab.com Text From mice to humans: developments in cancer immunoediting JO: J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=26241053 #FOAvip Cancer immunoediting explains the dual role by which the immune system can both suppress and/or promote tumor growth. Although cancer immunoediting was first demonstrated using mouse models of cancer, strong evidence that it occurs in human cancers is now accumulating. In particular, the importance of CD8+ T cells in cancer immunoediting has been shown, and more broadly in those tumors with an adaptive immune resistance phenotype. This Review describes the characteristics of the adaptive immune resistance tumor microenvironment and discusses data obtained in mouse and human settings. The role of other immune cells and factors influencing the effector function of tumor-specific CD8+ T cells is covered. We also discuss the temporal occurrence of cancer immunoediting in metastases and whether it differs from immunoediting in the primary tumor of origin. Twit Text FOAVip From mice to humans: developments in cancer immunoediting ????J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=26241053 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26241053 #FOAvip English Wikipedia <ref>{{Cite pmid|26241053}}</ref> From mice to humans: developments in cancer immunoediting #MMPMID26241053 Teng MW; Galon J; Fridman WH; Smyth MJ J Clin Invest 2015[Sep]; 125 (9): 3338-46 PMID26241053show ga Cancer immunoediting explains the dual role by which the immune system can both suppress and/or promote tumor growth. Although cancer immunoediting was first demonstrated using mouse models of cancer, strong evidence that it occurs in human cancers is now accumulating. In particular, the importance of CD8+ T cells in cancer immunoediting has been shown, and more broadly in those tumors with an adaptive immune resistance phenotype. This Review describes the characteristics of the adaptive immune resistance tumor microenvironment and discusses data obtained in mouse and human settings. The role of other immune cells and factors influencing the effector function of tumor-specific CD8+ T cells is covered. We also discuss the temporal occurrence of cancer immunoediting in metastases and whether it differs from immunoediting in the primary tumor of origin. äFrom mice to humans: developments in cancer immunoediting (epmc).pdf DeepDyve Pubget Overpricing