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10.1083/jcb.201702034

http://scihub22266oqcxt.onion/10.1083/jcb.201702034
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C5350528!5350528 !28228533
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suck abstract from ncbi


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pmid28228533
      J+Cell+Biol 2017 ; 216 (3 ): 531-533
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  • Fragile phagocytes: FMRP positively regulates engulfment activity #MMPMID28228533
  • Logan MA
  • J Cell Biol 2017[Mar]; 216 (3 ): 531-533 PMID28228533 show ga
  • Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.
  • |Animals [MESH]
  • |Drosophila Proteins/metabolism [MESH]
  • |Drosophila melanogaster/immunology/metabolism [MESH]
  • |Fragile X Mental Retardation Protein/*metabolism [MESH]
  • |Fragile X Syndrome/*immunology/*metabolism [MESH]
  • |Immunity, Innate/*immunology [MESH]


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