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2017 ; 2
(8
): 4143-4160
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Four-Analog Computation Based on DNA Strand Displacement
#MMPMID30023715
Zou C
; Wei X
; Zhang Q
; Liu C
; Zhou C
; Liu Y
ACS Omega
2017[Aug]; 2
(8
): 4143-4160
PMID30023715
show ga
DNA strand displacement plays an important role in biological computations. The
inherent advantages of parallelism, high storability, and cascading have resulted
in increased functional circuit realization of DNA strand displacement on the
nanoscale. Herein, we propose an analog computation with minus based on DNA
strand displacement. The addition, subtraction, multiplication, and division
gates as elementary gates could realize analog computation with minus. The
advantages of this proposal are the analog computation with negative value and
division computation. In this article, we provide the designs and principles of
these elementary gates and demonstrate gate performance by simulation.
Furthermore, to show the cascade property of gates, we computed a polynomial as
an example by these gates.