Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26756938
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26756938
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Dev+Dyn
2016 ; 245
(3
): 361-71
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Force transmission in epithelial tissues
#MMPMID26756938
Vasquez CG
; Martin AC
Dev Dyn
2016[Mar]; 245
(3
): 361-71
PMID26756938
show ga
In epithelial tissues, cells constantly generate and transmit forces between each
other. Forces generated by the actomyosin cytoskeleton regulate tissue shape and
structure and also provide signals that influence cells' decisions to divide,
die, or differentiate. Forces are transmitted across epithelia because cells are
mechanically linked through junctional complexes, and forces can propagate
through the cell cytoplasm. Here, we review some of the molecular mechanisms
responsible for force generation, with a specific focus on the actomyosin cortex
and adherens junctions. We then discuss evidence for how these mechanisms promote
cell shape changes and force transmission in tissues.