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2016 ; 32
(7
): 392-394
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Fishing for Function in the Human Gene Pool
#MMPMID27220646
Barozzi I
; Visel A
; Dickel DE
Trends Genet
2016[Jul]; 32
(7
): 392-394
PMID27220646
show ga
Identification and characterization of causal non-coding variants in human
genomes is challenging and requires substantial experimental resources. A new
study by Tehranchi et al. describes a cost-effective approach for accurate
mapping of molecular quantitative trait loci (QTLs) from pooled samples, a
powerful way to link disease-associated changes to molecular functions.