Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26032466
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
BMJ Clin Evid
2015[Jun]; 2015
(?): ? PMID26032466
show ga
INTRODUCTION: Between 50% and 77% of women may have fibroids, depending on the
method of diagnosis used. Fibroids may be asymptomatic, or may present with
menorrhagia, pain, mass and pressure effects, infertility, or recurrent pregnancy
loss. Risk factors for fibroids include obesity, having no children, and no
long-term use of the oral contraceptive pill. Fibroids tend to shrink or fibrose
after the menopause. METHODS AND OUTCOMES: We conducted a systematic review and
aimed to answer the following clinical question: What are the effects of
surgical/interventional radiological treatments in women with fibroids? We
searched: Medline, Embase, The Cochrane Library, and other important databases up
to May 2014 (Clinical Evidence reviews are updated periodically, please check our
website for the most up-to-date version of this review). We included harms alerts
from relevant organisations such as the US Food and Drug Administration (FDA) and
the UK Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: Five
studies were included. We performed a GRADE evaluation of the quality of evidence
for interventions. CONCLUSIONS: In this systematic review we present information
relating to the effectiveness and safety of the following interventions: magnetic
resonance-guided focused ultrasound surgery versus no/sham treatment; magnetic
resonance-guided focused ultrasound surgery versus other interventions
(hysterectomy, myomectomy, hysteroscopic resection, rollerball endometrial
ablation, thermal balloon ablation, thermal myolysis with laser); uterine artery
embolisation versus no/sham treatment; uterine artery embolisation versus
hysterectomy; uterine artery embolisation versus myomectomy; uterine artery
embolisation versus other interventions (magnetic resonance-guided focused
ultrasound surgery, hysteroscopic resection, rollerball endometrial ablation,
thermal balloon ablation, thermal myolysis with laser).
free
free
free
