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2016 ; 8
(3
): 266-73
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Fibrin sealant use in pilonidal sinus: Systematic review
#MMPMID27022454
Kayaalp C
; Ertugrul I
; Tolan K
; Sumer F
World J Gastrointest Surg
2016[Mar]; 8
(3
): 266-73
PMID27022454
show ga
AIM: To review the current data about the success rates of fibrin sealant use in
pilonidal disease. METHODS: Fibrin sealant can be used for different purposes in
pilonidal sinus treatment, such as filling in the sinus tracts, covering the open
wound after excision and lay-open treatment, or obliterating the subcutaneous
dead space before skin closure. We searched Pubmed, Google-Scholar, Ebsco-Host,
clinicaltrials, and Cochrane databases and found nine studies eligible for
analysis; these studies included a total of 217 patients (84% male, mean age 24.2
± 7.8). RESULTS: In cases where fibrin sealant was used to obliterate the
subcutaneous dead space, there was no reduction in wound complication rates (9.8%
vs 14.6%, P = 0.48). In cases where sealant was used to cover the laid-open area,
the wound healing time and patient comfort were reported better than in previous
studies (mean 17 d, 88% satisfaction). When fibrin sealant was used to fill the
sinus tracts, the recurrence rate was around 20%, despite the highly selected
grouping of patients. CONCLUSION: Consequently, using fibrin sealant to decrease
the risk of seroma formation was determined to be an ineffective course of
action. It was not advisable to fill the sinus tracts with fibrin sealant because
it was not superior to other cost-effective and minimally invasive treatments.
New comparative studies can be conducted to confirm the results of sealant use in
covering the laid-open area.
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