Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\30038660
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Drugs+Context
2018 ; 7
(ä): 212536
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Febrile seizures: an overview
#MMPMID30038660
Leung AK
; Hon KL
; Leung TN
Drugs Context
2018[]; 7
(ä): 212536
PMID30038660
show ga
BACKGROUND: Febrile seizures are the most common neurologic disorder in
childhood. Physicians should be familiar with the proper evaluation and
management of this common condition. OBJECTIVE: To provide an update on the
current understanding, evaluation, and management of febrile seizures. METHODS: A
PubMed search was completed in Clinical Queries using the key terms 'febrile
convulsions' and 'febrile seizures'. The search strategy included meta-analyses,
randomized controlled trials, clinical trials, observational studies, and
reviews. RESULTS: Febrile seizures, with a peak incidence between 12 and 18
months of age, likely result from a vulnerability of the developing central
nervous system to the effects of fever, in combination with an underlying genetic
predisposition and environmental factors. The majority of febrile seizures occur
within 24 hours of the onset of the fever. Febrile seizures can be simple or
complex. Clinical judgment based on variable presentations must direct the
diagnostic studies which are usually not necessary in the majority of cases. A
lumbar puncture should be considered in children younger than 12 months of age or
with suspected meningitis. Children with complex febrile seizures are at risk of
subsequent epilepsy. Approximately 30-40% of children with a febrile seizure will
have a recurrence during early childhood. The prognosis is favorable as the
condition is usually benign and self-limiting. Intervention to stop the seizure
often is unnecessary. CONCLUSION: Continuous preventative antiepileptic therapy
for the prevention of recurrent febrile seizures is not recommended. The use of
intermittent anticonvulsant therapy is not routinely indicated. Antipyretics have
no role in the prevention of febrile seizures.
free
free
free
