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10.4161/23723556.2014.995041

http://scihub22266oqcxt.onion/10.4161/23723556.2014.995041
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C4905318!4905318 !27308481
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suck abstract from ncbi


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pmid27308481
      Mol+Cell+Oncol 2015 ; 2 (3 ): e995041
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  • Fbw7 and Usp28 - enemies and allies #MMPMID27308481
  • Taranets L ; Zhu J ; Xu W ; Popov N
  • Mol Cell Oncol 2015[Jul]; 2 (3 ): e995041 PMID27308481 show ga
  • The Usp28 deubiquitinase antagonizes Fbw7-mediated turnover of multiple oncoproteins, including Myc, Jun, and Notch, and promotes tumorigenesis in the intestine. Our recent study reveals that Usp28 also counteracts autocatalytic ubiquitination of Fbw7, suggesting a complex role for Usp28 in the regulation of Fbw7 activity and tumor development.
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