Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29744128
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29744128
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Oxf+Med+Case+Reports
2018 ; 2018
(5
): omy010
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Fatal case of amoebic encephalitis masquerading as herpes
#MMPMID29744128
Baral R
; Vaidya B
Oxf Med Case Reports
2018[May]; 2018
(5
): omy010
PMID29744128
show ga
Primary amoebic meningoencephalitis (PAM) is a rare, fulminating, hemorrhagic
infection of the brain caused by Naegleria fowleri, a thermophilic, free-living
amoeba. A 74-year male presented with sudden severe global headache and fever
with features of anomic aphasia. Magnetic resonance imaging (MRI) suggested
herpes encephalitis and acyclovir (IV) was started but the patient developed
altered sensorium, agitation and progressive weakness of lower limbs with gradual
truncal weakness. Repeat MRI showed increase in lesion size and edema with
confluent blood areas. Dexamethasone showed significant improvement. Ten days
after completion of acyclovir, there was recurrence of altered sensorium with
seizures. Repeat MRI showed new lesions appearing. Excisional biopsy of brain
confirmed N. fowleri. Amphotericin B and miltefosin was started but patient
succumbed to his illness after 10 days. This is a first case of PAM in Nepal,
involving elderly immune-competent male without environmental exposure to
freshwater, mimicking as herpes encephalitis.