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10.1093/bioadv/vbaf238 http://scihub22266oqcxt.onion/10.1093/bioadv/vbaf238 C12624442!12624442 !41262969     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=41262969 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Bioinform+Adv 2025 ; 5 (1 ): vbaf238 Nephropedia Template TP {{tp|p=41262969 |t=2025. FastGA: fast genome alignment |pdf=|usr=}}{{41262969 }} gab.com Text FastGA: fast genome alignment JO: Bioinform Adv http://www.kidney.de/pget.php?&tw=1&pmid=41262969 #FOAvip MOTIVATION: FastGA finds alignments between two genome sequences more than an order of magnitude faster than previous methods that have comparable sensitivity. Its speed is due to (i) a fully cache-local architecture involving only MSD radix sorts and merges, (ii) an algorithm for finding adaptive seed hits in a linear merge of sorted k-mer tables, and (iii) a variant of the Myers adaptive wave algorithm to find alignments around a chain of seed hits. It further stores alignments in a fraction of the space of a conventional CIGAR string using a trace-point encoding and our ONEcode data system introduced here. RESULTS: For example, two 2 Gbp bat genomes are compared in 2.1?min with eight threads on an Apple laptop using 5.7 GB of memory and producing 1.05 million alignments covering 60% of each genome. Our ALN format file occupies 66 MB and in just 6?s can be converted to a standard 1.03 GB PAF file. AVAILABILITY AND IMPLEMENTATION: FastGA is freely available at GitHub: http://www.github.com/thegenemyers/FASTGA along with utilities for viewing inputs, intermediates, and outputs and transforming ALN files to PSL or PAF with or without CIGAR strings and common formats. There is also a utility to chain FastGA's alignments and display them in a dot-plot view in PostScript files. Twit Text FOAVip FastGA: fast genome alignment ????Bioinform Adv http://www.kidney.de/pget.php?&tw=1&pmid=41262969 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=41262969 #FOAvip English Wikipedia <ref>{{Cite pmid|41262969 }}</ref> FastGA: fast genome alignment #MMPMID41262969 Myers G ; Durbin R ; Zhou C Bioinform Adv 2025[]; 5 (1 ): vbaf238 PMID41262969 show ga MOTIVATION: FastGA finds alignments between two genome sequences more than an order of magnitude faster than previous methods that have comparable sensitivity. Its speed is due to (i) a fully cache-local architecture involving only MSD radix sorts and merges, (ii) an algorithm for finding adaptive seed hits in a linear merge of sorted k-mer tables, and (iii) a variant of the Myers adaptive wave algorithm to find alignments around a chain of seed hits. It further stores alignments in a fraction of the space of a conventional CIGAR string using a trace-point encoding and our ONEcode data system introduced here. RESULTS: For example, two 2 Gbp bat genomes are compared in 2.1?min with eight threads on an Apple laptop using 5.7 GB of memory and producing 1.05 million alignments covering 60% of each genome. Our ALN format file occupies 66 MB and in just 6?s can be converted to a standard 1.03 GB PAF file. AVAILABILITY AND IMPLEMENTATION: FastGA is freely available at GitHub: http://www.github.com/thegenemyers/FASTGA along with utilities for viewing inputs, intermediates, and outputs and transforming ALN files to PSL or PAF with or without CIGAR strings and common formats. There is also a utility to chain FastGA's alignments and display them in a dot-plot view in PostScript files. ?FastGA: fast genome alignment (epmc).pdf DeepDyve Pubget Overpricing