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10.1055/s-0036-1579760

http://scihub22266oqcxt.onion/10.1055/s-0036-1579760
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C4918699!4918699!27617147
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suck abstract from ncbi


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pmid27617147      J+Pediatr+Genet 2016 ; 5 (2): 78-83
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  • Familial Adenomatous Polyposis #MMPMID27617147
  • Waller A; Findeis S; Lee MJ
  • J Pediatr Genet 2016[Jun]; 5 (2): 78-83 PMID27617147show ga
  • Familial adenomatous polyposis (FAP), caused by a germline mutation in the adenomatous polyposis coli (APC) gene on chromosome 5q21, is an autosomal dominant disorder characterized by hundreds to thousands of adenomas throughout the gastrointestinal tract. A variety of extraintestinal manifestations, including thyroid, soft tissue, and brain tumors, may also be present. These patients inevitably develop colorectal carcinoma by the fourth decade of life. In this review, the pathology, epidemiology, and genetic features of FAP are discussed.
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