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10.15252/emmm.201606932 http://scihub22266oqcxt.onion/10.15252/emmm.201606932 C5376756!5376756 !28242755     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28242755 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       EMBO+Mol+Med 2017 ; 9 (4 ): 448-461 Nephropedia Template TP {{tp|p=28242755 |t=2017. Faecal microbiota transplantation protects against radiation-induced toxicity |pdf=|usr=}}{{28242755 }} gab.com Text Faecal microbiota transplantation protects against radiation-induced toxicity JO: EMBO Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=28242755 #FOAvip Severe radiation exposure may cause acute radiation syndrome, a possibly fatal condition requiring effective therapy. Gut microbiota can be manipulated to fight against many diseases. We explored whether intestinal microbe transplantation could alleviate radiation-induced toxicity. High-throughput sequencing showed that gastrointestinal bacterial community composition differed between male and female mice and was associated with susceptibility to radiation toxicity. Faecal microbiota transplantation (FMT) increased the survival rate of irradiated animals, elevated peripheral white blood cell counts and improved gastrointestinal tract function and intestinal epithelial integrity in irradiated male and female mice. FMT preserved the intestinal bacterial composition and retained mRNA and long non-coding RNA expression profiles of host small intestines in a sex-specific fashion. Despite promoting angiogenesis, sex-matched FMT did not accelerate the proliferation of cancer cells in vivo FMT might serve as a therapeutic to mitigate radiation-induced toxicity and improve the prognosis of tumour patients after radiotherapy. Twit Text FOAVip Faecal microbiota transplantation protects against radiation-induced toxicity ????EMBO Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=28242755 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28242755 #FOAvip English Wikipedia <ref>{{Cite pmid|28242755 }}</ref> Faecal microbiota transplantation protects against radiation-induced toxicity #MMPMID28242755 Cui M ; Xiao H ; Li Y ; Zhou L ; Zhao S ; Luo D ; Zheng Q ; Dong J ; Zhao Y ; Zhang X ; Zhang J ; Lu L ; Wang H ; Fan S EMBO Mol Med 2017[Apr]; 9 (4 ): 448-461 PMID28242755 show ga Severe radiation exposure may cause acute radiation syndrome, a possibly fatal condition requiring effective therapy. Gut microbiota can be manipulated to fight against many diseases. We explored whether intestinal microbe transplantation could alleviate radiation-induced toxicity. High-throughput sequencing showed that gastrointestinal bacterial community composition differed between male and female mice and was associated with susceptibility to radiation toxicity. Faecal microbiota transplantation (FMT) increased the survival rate of irradiated animals, elevated peripheral white blood cell counts and improved gastrointestinal tract function and intestinal epithelial integrity in irradiated male and female mice. FMT preserved the intestinal bacterial composition and retained mRNA and long non-coding RNA expression profiles of host small intestines in a sex-specific fashion. Despite promoting angiogenesis, sex-matched FMT did not accelerate the proliferation of cancer cells in vivo FMT might serve as a therapeutic to mitigate radiation-induced toxicity and improve the prognosis of tumour patients after radiotherapy. |*Fecal Microbiota Transplantation [MESH] |Animals [MESH] |Female [MESH] |Intestinal Mucosa/pathology [MESH] |Intestine, Small/pathology [MESH] |Male [MESH] |Mice [MESH] |Radiation Injuries, Experimental/pathology/*prevention & control [MESH] |Radiation Protection/*methods [MESH]Faecal microbiota transplantation protects against radiation-induced t(epmc).pdf DeepDyve Pubget Overpricing