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2015 ; 2015
(ä): 347920
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Factors Associated with Poststroke Fatigue: A Systematic Review
#MMPMID26101691
Ponchel A
; Bombois S
; Bordet R
; Hénon H
Stroke Res Treat
2015[]; 2015
(ä): 347920
PMID26101691
show ga
Background. Poststroke fatigue (PSF) is a frequent, disabling symptom that lacks
a consensual definition and a standardized evaluation method. The (multiple)
causes of PSF have not been formally characterized. Objective. To identify
factors associated with PSF. Method. A systematic review of articles referenced
in MEDLINE. Only original studies having measured PSF and potentially associated
factors were included. Data was extracted from articles using predefined data
fields. Results. Although PSF tends to be more frequent in female patients and
older patients, sociodemographic factors do not appear to have a major impact.
There are strong associations between PSF and emotional disturbances (such as
depression and anxiety). PSF may also be linked to attentional disturbances
(mainly slowing in processing speed). The literature data have failed to
demonstrate a clear impact of the type and severity of stroke. It has been
suggested that PSF results from alterations in the frontothalamostriatal system
and/or inflammatory processes. Pain, sleep disorders, and prestroke fatigue also
appeared to be associated with PSF. Implications. A better understanding of PSF
may improve stroke patient care and facilitate the development of effective
treatments.