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http://scihub22266oqcxt.onion/ C5612190!5612190 !28955186     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28955186 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Yale+J+Biol+Med 2017 ; 90 (3 ): 481-491 Nephropedia Template TP {{tp|p=28955186 |t=2017. Extracellular Vesicles: Evolutionarily Conserved Mediators of Intercellular Communication |pdf=|usr=}}{{28955186 }} gab.com Text Extracellular Vesicles: Evolutionarily Conserved Mediators of Intercellular Communication JO: Yale J Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=28955186 #FOAvip Extracellular vesicles (EV) are sub-micron circulating vesicles found in all bodily fluids and in all species so far tested. They have also recently been identified in seawater and it has further been shown that they are released from microorganisms and may participate in interspecies communication in the gut. EV are typically composed of a lipid bilayer formed from the plasma membrane and which encases a cargo that can include genetic material, proteins, and lipids. At least two different processes of formation and release have been described in mammalian cells. The exosome population (50 to 150nm size) are produced via a lyso-endosomal pathway, while microvesicles (100 to 1000nm) are formed by budding of the plasma membrane in a calcium dependent process. Both pathways are highly regulated and appear to be conserved amongst different species. EV release has been shown to be upregulated in a number of human chronic diseases including cardiovascular disease, metabolic disorders, obesity, and cancer; evaluation of their presence in veterinary samples may aid diagnosis in the future. This review will provide insight into the formation of EV and their detection in bodily fluids from different veterinary species and how they may provide a novel addition to the veterinary toolkit of the future. Twit Text FOAVip Extracellular Vesicles: Evolutionarily Conserved Mediators of Intercellular Communication ????Yale J Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=28955186 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28955186 #FOAvip English Wikipedia <ref>{{Cite pmid|28955186 }}</ref> Extracellular Vesicles: Evolutionarily Conserved Mediators of Intercellular Communication #MMPMID28955186 Lawson C ; Kovacs D ; Finding E ; Ulfelder E ; Luis-Fuentes V Yale J Biol Med 2017[Sep]; 90 (3 ): 481-491 PMID28955186 show ga Extracellular vesicles (EV) are sub-micron circulating vesicles found in all bodily fluids and in all species so far tested. They have also recently been identified in seawater and it has further been shown that they are released from microorganisms and may participate in interspecies communication in the gut. EV are typically composed of a lipid bilayer formed from the plasma membrane and which encases a cargo that can include genetic material, proteins, and lipids. At least two different processes of formation and release have been described in mammalian cells. The exosome population (50 to 150nm size) are produced via a lyso-endosomal pathway, while microvesicles (100 to 1000nm) are formed by budding of the plasma membrane in a calcium dependent process. Both pathways are highly regulated and appear to be conserved amongst different species. EV release has been shown to be upregulated in a number of human chronic diseases including cardiovascular disease, metabolic disorders, obesity, and cancer; evaluation of their presence in veterinary samples may aid diagnosis in the future. This review will provide insight into the formation of EV and their detection in bodily fluids from different veterinary species and how they may provide a novel addition to the veterinary toolkit of the future. |Animals [MESH] |Cats [MESH] |Cattle [MESH] |Cell Communication/*physiology [MESH] |Dogs [MESH] |Extracellular Vesicles/*metabolism [MESH]Extracellular Vesicles: Evolutionarily Conserved Mediators of Intercel(epmc).pdf DeepDyve Pubget Overpricing