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10.1111/all.13086

http://scihub22266oqcxt.onion/10.1111/all.13086
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suck abstract from ncbi


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pmid27859351
      Allergy 2017 ; 72 (4 ): 534-544
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  • Exosomes in immunoregulation of chronic lung diseases #MMPMID27859351
  • Hough KP ; Chanda D ; Duncan SR ; Thannickal VJ ; Deshane JS
  • Allergy 2017[Apr]; 72 (4 ): 534-544 PMID27859351 show ga
  • Exosomes are nano-sized, membrane-bound vesicles released from cells that transport cargo including DNA, RNA, and proteins, between cells as a form of intercellular communication. In addition to their role in intercellular communication, exosomes are beginning to be appreciated as agents of immunoregulation that can modulate antigen presentation, immune activation, suppression, and surveillance. This article summarizes how these multifaceted functions of exosomes may promote development and/or progression of chronic inflammatory lung diseases including asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis. The potential of exosomes as a novel therapeutic is also discussed.
  • |*Immunomodulation [MESH]
  • |Animals [MESH]
  • |Biological Transport [MESH]
  • |Biomarkers [MESH]
  • |Chronic Disease [MESH]
  • |Exosomes/*metabolism [MESH]
  • |Gene Expression Regulation [MESH]
  • |Homeostasis [MESH]
  • |Humans [MESH]
  • |Lung Diseases/*etiology/*metabolism/pathology/therapy [MESH]
  • |Respiratory Tract Diseases/etiology/metabolism/pathology/therapy [MESH]
  • |Signal Transduction [MESH]


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