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10.15698/mic2015.07.215 http://scihub22266oqcxt.onion/10.15698/mic2015.07.215 C5349173!5349173 !28357301     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28357301 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Microb+Cell 2015 ; 2 (7 ): 256-258 Nephropedia Template TP {{tp|p=28357301 |t=2015. Evolutionary rewiring of bacterial regulatory networks |pdf=|usr=}}{{28357301 }} gab.com Text Evolutionary rewiring of bacterial regulatory networks JO: Microb Cell http://www.kidney.de/pget.php?&tw=1&pmid=28357301 #FOAvip Bacteria have evolved complex regulatory networks that enable integration of multiple intracellular and extracellular signals to coordinate responses to environmental changes. However, our knowledge of how regulatory systems function and evolve is still relatively limited. There is often extensive homology between components of different networks, due to past cycles of gene duplication, divergence, and horizontal gene transfer, raising the possibility of cross-talk or redundancy. Consequently, evolutionary resilience is built into gene networks - homology between regulators can potentially allow rapid rescue of lost regulatory function across distant regions of the genome. In our recent study [Taylor, et al. Science (2015), 347(6225)] we find that mutations that facilitate cross-talk between pathways can contribute to gene network evolution, but that such mutations come with severe pleiotropic costs. Arising from this work are a number of questions surrounding how this phenomenon occurs. Twit Text FOAVip Evolutionary rewiring of bacterial regulatory networks ????Microb Cell http://www.kidney.de/pget.php?&tw=1&pmid=28357301 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28357301 #FOAvip English Wikipedia <ref>{{Cite pmid|28357301 }}</ref> Evolutionary rewiring of bacterial regulatory networks #MMPMID28357301 Taylor TB ; Mulley G ; McGuffin LJ ; Johnson LJ ; Brockhurst MA ; Arseneault T ; Silby MW ; Jackson RW Microb Cell 2015[Jul]; 2 (7 ): 256-258 PMID28357301 show ga Bacteria have evolved complex regulatory networks that enable integration of multiple intracellular and extracellular signals to coordinate responses to environmental changes. However, our knowledge of how regulatory systems function and evolve is still relatively limited. There is often extensive homology between components of different networks, due to past cycles of gene duplication, divergence, and horizontal gene transfer, raising the possibility of cross-talk or redundancy. Consequently, evolutionary resilience is built into gene networks - homology between regulators can potentially allow rapid rescue of lost regulatory function across distant regions of the genome. In our recent study [Taylor, et al. Science (2015), 347(6225)] we find that mutations that facilitate cross-talk between pathways can contribute to gene network evolution, but that such mutations come with severe pleiotropic costs. Arising from this work are a number of questions surrounding how this phenomenon occurs. äEvolutionary rewiring of bacterial regulatory networks (epmc).pdf DeepDyve Pubget Overpricing