Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26446368
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26446368
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Evodevo
2015 ; 6
(ä): 30
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Evolution of the notochord
#MMPMID26446368
Annona G
; Holland ND
; D'Aniello S
Evodevo
2015[]; 6
(ä): 30
PMID26446368
show ga
A notochord is characteristic of developing chordates (which comprise amphioxus,
tunicates and vertebrates), and, more arguably, is also found in some other
animals. Although notochords have been well reviewed from a developmental genetic
point of view, there has heretofore been no adequate survey of the dozen or so
scenarios accounting for their evolutionary origin. Advances in molecular
phylogenetics and developmental genetics have, on the one hand, failed to support
many of these ideas (although, it is not impossible that some of these rejects
may yet, at least in part, return to favor). On the other hand, current molecular
approaches have actually stimulated the revival of two of the old proposals:
first that the notochord is a novelty that arose in the chordates, and second
that it is derived from a homologous structure, the axochord, that was present in
annelid-like ancestors. In the long term, choosing whether the notochord is a
chordate novelty or a legacy from an ancient annelid (or perhaps an evolutionary
derivative from precursors yet to be proposed) will probably require descriptions
of gene regulatory networks involved in the development of notochords and
notochord-like structures in a wide spectrum of animals. For now, one-way forward
will be studies of all aspects of the biology of enteropneust hemichordates, a
group widely thought to be the key to understanding the evolutionary origin of
the chordates.