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2015 ; 11
(ä): 1687-96
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Evidence-based treatments for cluster headache
#MMPMID26635477
Gooriah R
; Buture A
; Ahmed F
Ther Clin Risk Manag
2015[]; 11
(ä): 1687-96
PMID26635477
show ga
Cluster headache (CH), one of the most painful syndromes known to man, is managed
with acute and preventive medications. The brief duration and severity of the
attacks command the use of rapid-acting pain relievers. Inhalation of oxygen and
subcutaneous sumatriptan are the two most effective acute therapeutic options for
sufferers of CH. Several preventive medications are available, the most effective
of which is verapamil. However, most of these agents are not backed by strong
clinical evidence. In some patients, these options can be ineffective, especially
in those who develop chronic CH. Surgical procedures for the chronic refractory
form of the disorder should then be contemplated, the most promising of which is
hypothalamic deep brain stimulation. We hereby review the pathogenesis of CH and
the evidence behind the treatment options for this debilitating condition.