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2018 ; 44
(3
): 268-273
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Evaluation of renal tumors in children
#MMPMID29733801
Bozlu G
; Ç?tak EÇ
Turk J Urol
2018[May]; 44
(3
): 268-273
PMID29733801
show ga
OBJECTIVE: Renal tumors are not uncommon in children. In this study, we aimed to
evaluate the clinical and pathological features of renal tumors in children.
MATERIAL AND METHODS: Between January 2008 and December 2017, the records of
children with renal tumors in our institution were retrospectively analyzed. Data
collected were composed of demographic and clinical characteristics including
gender, age at time of diagnosis, symptoms, laterality of the tumor and
pathological evaluation. RESULTS: A total of 48 children with renal tumor (28
males and 20 females) were included in the study. They were diagnosed at mean age
of 53.26±46.64 months (range: 1-192) and the mean follow-up period was
73.45±48.92 months (range: 6-120). The most common symptom was a lump or mass in
the area of the kidneys (45.8%), abdominal pain and hematuria (14.6%). Four
patients (8.3%) were diagnosed at antenatal period. 68.8% of the children had
Wilms tumor and the major histological groups of non-Wilms renal tumors were
renal cell carcinoma (12.5%), congenital mesoblastic nephroma (10.4%) and
angiomyolipoma (4.2%). 10.4% of the children had bilateral tumors and one
patients had Wilms tumor with horseshoe kidney. 87.5% of the children were
treated with surgery and of those 7 (14.5%) underwent nephron-sparing surgery.
The patients had chemotherapy and radiotherapy (83.3% and 41.7%, respectively).
Seven patients (14.6%) died during follow-up. CONCLUSION: Wilms tumor is the most
common pediatric renal neoplasm. On the other hand, we showed that considerable
number of children with renal tumors had non-Wilms tumors including renal cell
carcinoma, congenital mesoblastic nephroma and angiomyolipoma.
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