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10.1038/nmeth.3098

http://scihub22266oqcxt.onion/10.1038/nmeth.3098
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C4180802!4180802 !25194848
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suck abstract from ncbi


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pmid25194848
      Nat+Methods 2014 ; 11 (10 ): 1058-63
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  • Evaluation and statistical inference for human connectomes #MMPMID25194848
  • Pestilli F ; Yeatman JD ; Rokem A ; Kay KN ; Wandell BA
  • Nat Methods 2014[Oct]; 11 (10 ): 1058-63 PMID25194848 show ga
  • Diffusion-weighted imaging coupled with tractography is currently the only method for in vivo mapping of human white-matter fascicles. Tractography takes diffusion measurements as input and produces the connectome, a large collection of white-matter fascicles, as output. We introduce a method to evaluate the evidence supporting connectomes. Linear fascicle evaluation (LiFE) takes any connectome as input and predicts diffusion measurements as output, using the difference between the measured and predicted diffusion signals to quantify the prediction error. We use the prediction error to evaluate the evidence that supports the properties of the connectome, to compare tractography algorithms and to test hypotheses about tracts and connections.
  • |Algorithms [MESH]
  • |Brain Mapping/methods [MESH]
  • |Brain/*pathology [MESH]
  • |Cognition [MESH]
  • |Computational Biology/*methods [MESH]
  • |Connectome/*methods [MESH]
  • |Data Interpretation, Statistical [MESH]
  • |Humans [MESH]
  • |Magnetic Resonance Imaging/methods [MESH]
  • |Nerve Fibers, Myelinated/*physiology [MESH]
  • |Probability [MESH]
  • |Reproducibility of Results [MESH]
  • |Software [MESH]


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