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1991 ; 6
(2
): 58-63
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Etiologic considerations of nonspecific pleuritis
#MMPMID1807366
Kim NJ
; Hong SC
; Kim JO
; Suhr JW
; Kim SY
; Ro HK
Korean J Intern Med
1991[Jul]; 6
(2
): 58-63
PMID1807366
show ga
Twenty-three patients with nonspecific pleuritis were studied to determine
clinical outcome. After a mean follow-up period of 6 months (1 to 36 months), a
diagnosis was reached in 17 patients, while 6 patients remained unknown. The
causes of the nonspecific pleuritis diagnosed on initial pleural biopsy were
tuberculosis (11 patients, 48%), neoplasm (2 patients, 8.7%), parapneumonic
effusion (1 patient), subphrenic abscess (1 patient), congestive heart failure (1
patients), and nephrotic syndrome (1 patient). The diagnosis was made by
therapeutic trials (tuberculosis: 11 patients, parapneumonic effusion: 1 patient,
congestive heart failure: 1 patient), by repeat pleural biopsy in 1 hepatoma, by
open thoractomy in 1 lung cancer, by exploratory laparotomy in 1 subphrenic
abscess, and by kidney biopsy in 1 nephrotic syndrome. The WBC counts (more than
2,000/mm3) and lymphocyte percentage (more than 60%) in the pleural fluid were
significantly elevated in the patients with tuberculosis compared to those with
malignant pleurisy, and other laboratory data were meaningless. As a result of
this investigation, we suggest that tuberculous pleurisy is the most common cause
of nonspecific pleuritis in Korea and that therapeutic trial with antituberculous
medication for patients with high WBC count and lymphocyte percent in pleural
fluid can help to locate the nonspecific pleuritis.