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10.1111/acer.12342 http://scihub22266oqcxt.onion/10.1111/acer.12342 C3984360!3984360 !24460901     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24460901 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24460901 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Alcohol+Clin+Exp+Res 2014 ; 38 (4 ): 1184-92 Nephropedia Template TP {{tp|p=24460901 |t=2014. Ethanol induces conditioned social preference in male mice |pdf=|usr=}}{{24460901 }} gab.com Text Ethanol induces conditioned social preference in male mice JO: Alcohol Clin Exp Res http://www.kidney.de/pget.php?&tw=1&pmid=24460901 #FOAvip BACKGROUND: Affiliative social interactions promote alcohol consumption, and alcohol also promotes affiliative behavior. Furthermore, for most species, moderate doses of ethanol (EtOH) and social affiliation are each rewarding. However, animal studies of drug and EtOH reward typically test individuals in isolation. To address social dimensions of EtOH reward, this study tested EtOH-induced conditioned social preference in male C57BL/6 mice with (ORCHX+T) and without (ORCHX) testosterone. METHODS: ORCHX+T males received EtOH (0, 1, 2, or 3 g/kg) intraperitoneally and were paired 4× for 30 minutes each with 1 of 2 stimulus males: with the CS- stimulus male after saline injection and with the CS+ male following EtOH. After pairing, time spent with CS+ and CS- males was measured in a 10-minute test. RESULTS: ORCHX+T test males showed conditioned preference for the CS+ male in response to 3 g/kg EtOH (change in preference: +71.3 ± 30.0 s/10 min, p < 0.05), but not for 0, 1, or 2 g/kg. By contrast, ORCHX males did not demonstrate conditioned preference for 3 g/kg EtOH (+16.0 ± 24.3 s/10 min, p > 0.05). In separate groups of mice, stimulus males (IS+) received EtOH during pairing to determine whether test mice prefer another intoxicated mouse. Both ORCHX+T and ORCHX test mice showed an increase in preference score for the IS+ mouse (ORCHX+T: +68.1 ± 24.0 seconds; ORCHX: +58.9 ± 19.6 seconds, p < 0.05). CONCLUSIONS: These data demonstrate that EtOH promotes social preference in male mice, as it does in females. Testosterone enhances this effect. Twit Text FOAVip Ethanol induces conditioned social preference in male mice ????Alcohol Clin Exp Res http://www.kidney.de/pget.php?&tw=1&pmid=24460901 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24460901 #FOAvip English Wikipedia <ref>{{Cite pmid|24460901 }}</ref> Ethanol induces conditioned social preference in male mice #MMPMID24460901 Kent K ; Butler K ; Wood RI Alcohol Clin Exp Res 2014[Apr]; 38 (4 ): 1184-92 PMID24460901 show ga BACKGROUND: Affiliative social interactions promote alcohol consumption, and alcohol also promotes affiliative behavior. Furthermore, for most species, moderate doses of ethanol (EtOH) and social affiliation are each rewarding. However, animal studies of drug and EtOH reward typically test individuals in isolation. To address social dimensions of EtOH reward, this study tested EtOH-induced conditioned social preference in male C57BL/6 mice with (ORCHX+T) and without (ORCHX) testosterone. METHODS: ORCHX+T males received EtOH (0, 1, 2, or 3 g/kg) intraperitoneally and were paired 4× for 30 minutes each with 1 of 2 stimulus males: with the CS- stimulus male after saline injection and with the CS+ male following EtOH. After pairing, time spent with CS+ and CS- males was measured in a 10-minute test. RESULTS: ORCHX+T test males showed conditioned preference for the CS+ male in response to 3 g/kg EtOH (change in preference: +71.3 ± 30.0 s/10 min, p < 0.05), but not for 0, 1, or 2 g/kg. By contrast, ORCHX males did not demonstrate conditioned preference for 3 g/kg EtOH (+16.0 ± 24.3 s/10 min, p > 0.05). In separate groups of mice, stimulus males (IS+) received EtOH during pairing to determine whether test mice prefer another intoxicated mouse. Both ORCHX+T and ORCHX test mice showed an increase in preference score for the IS+ mouse (ORCHX+T: +68.1 ± 24.0 seconds; ORCHX: +58.9 ± 19.6 seconds, p < 0.05). CONCLUSIONS: These data demonstrate that EtOH promotes social preference in male mice, as it does in females. Testosterone enhances this effect. |*Social Behavior [MESH] |Animals [MESH] |Conditioning, Psychological/*drug effects/physiology [MESH] |Dose-Response Relationship, Drug [MESH] |Ethanol/*administration & dosage [MESH] |Male [MESH] |Mice [MESH]Ethanol induces conditioned social preference in male mice (epmc).pdf DeepDyve Pubget Overpricing