Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.cub.2009.10.067 http://scihub22266oqcxt.onion/10.1016/j.cub.2009.10.067 C4867117!4867117 !20064425     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20064425 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\20064425 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Biol 2009 ; 19 (24 ): R1126-32 Nephropedia Template TP {{tp|p=20064425 |t=2009. Establishment of sister chromatid cohesion |pdf=|usr=}}{{20064425 }} gab.com Text Establishment of sister chromatid cohesion JO: Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=20064425 #FOAvip The process of sister chromatid pairing, or cohesion establishment, is coupled to DNA replication and fundamental to proper chromosome segregation and cell viability. In the past year, several articles have provided important new insights into cohesion establishment, an activity predicated on the acetyltransferase Ctf7/Eco1. Here, I review new findings that the conversion of chromatid-bound cohesins into a cohesion-competent state involves Ctf7/Eco1-mediated acetylation of the cohesin subunit Smc3. These studies further explore an anti-establishment activity that involves the binding of accessory factors WAPL/Rad61 and Pds5 to the cohesin subunit Scc3/Irr1. The anti-establishment activity of WAPL/Rad61 and Pds5 is temporarily relaxed by Ctf7/Eco1 during S phase to promote sister chromatid pairing. These findings are likely to be of clinical relevance, given the role of cohesion pathways in a wide range of disease states. Twit Text FOAVip Establishment of sister chromatid cohesion ????Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=20064425 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20064425 #FOAvip English Wikipedia <ref>{{Cite pmid|20064425 }}</ref> Establishment of sister chromatid cohesion #MMPMID20064425 Skibbens RV Curr Biol 2009[Dec]; 19 (24 ): R1126-32 PMID20064425 show ga The process of sister chromatid pairing, or cohesion establishment, is coupled to DNA replication and fundamental to proper chromosome segregation and cell viability. In the past year, several articles have provided important new insights into cohesion establishment, an activity predicated on the acetyltransferase Ctf7/Eco1. Here, I review new findings that the conversion of chromatid-bound cohesins into a cohesion-competent state involves Ctf7/Eco1-mediated acetylation of the cohesin subunit Smc3. These studies further explore an anti-establishment activity that involves the binding of accessory factors WAPL/Rad61 and Pds5 to the cohesin subunit Scc3/Irr1. The anti-establishment activity of WAPL/Rad61 and Pds5 is temporarily relaxed by Ctf7/Eco1 during S phase to promote sister chromatid pairing. These findings are likely to be of clinical relevance, given the role of cohesion pathways in a wide range of disease states. |*Models, Biological [MESH] |Acetylation [MESH] |Acetyltransferases/*metabolism [MESH] |Animals [MESH] |Cell Cycle Proteins/*metabolism [MESH] |Chromatids/*metabolism [MESH] |Chromosomal Proteins, Non-Histone/*metabolism [MESH] |Cohesins [MESH] |DNA Replication/*physiology [MESH] |Humans [MESH] |Nuclear Proteins/*metabolism [MESH] |S Phase/*physiology [MESH] |Saccharomyces cerevisiae Proteins/*metabolism [MESH]Establishment of sister chromatid cohesion (epmc).pdf DeepDyve Pubget Overpricing