Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26617944
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Int J Clin Exp Pathol
2015[]; 8
(9
): 11884-94
PMID26617944
show ga
Oral cancer is one of the 10 most common cancers in the world, with a delayed
clinical detection, poor prognosis, without specific biomarkers for the disease
and expensive therapeutic alternatives. This review aims to present the
fundamental aspects of this cancer, focused on squamous cell carcinoma of the
oral cavity (OSCC), moving from its definition and epidemiological aspects,
addressing the oral carcinogenesis, oral potentially malignant disorders,
epithelial precursor lesions and experimental methods for its study, therapies
and future challenges. Oral cancer is a preventable disease, risk factors and
natural history is already being known, where biomedical sciences and dentistry
in particular are likely to improve their poor clinical indicators.