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10.1016/j.cbpa.2017.01.012 http://scihub22266oqcxt.onion/10.1016/j.cbpa.2017.01.012 C5850962!5850962 !28213207     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28213207 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Chem+Biol 2017 ; 36 (ä): 70-76 Nephropedia Template TP {{tp|p=28213207 |t=2017. Epimetabolites: discovering metabolism beyond building and burning |pdf=|usr=}}{{28213207 }} gab.com Text Epimetabolites: discovering metabolism beyond building and burning JO: Curr Opin Chem Biol http://www.kidney.de/pget.php?&tw=1&pmid=28213207 #FOAvip Enzymatic transformations of primary, canonical metabolites generate active biomolecules that regulate important cellular and physiological processes. Roles include regulation of histone demethylation in epigenetics, inflammation in tissue injury, insulin sensitivity, cancer cell invasion, stem cell pluripotency status, inhibition of nitric oxide signaling and others. Such modified compounds, defined as epimetabolites, have functions distinct from classic hormones as well as removed from generic anabolism and catabolism. Epimetabolites are discovered by untargeted metabolomics using liquid- or gas chromatography-high resolution mass spectrometry and structurally annotated by in-silico fragmentation prediction tools. Their specific biological functions are subsequently investigated by targeted metabolomics methods. Twit Text FOAVip Epimetabolites: discovering metabolism beyond building and burning ????Curr Opin Chem Biol http://www.kidney.de/pget.php?&tw=1&pmid=28213207 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28213207 #FOAvip English Wikipedia <ref>{{Cite pmid|28213207 }}</ref> Epimetabolites: discovering metabolism beyond building and burning #MMPMID28213207 Showalter MR ; Cajka T ; Fiehn O Curr Opin Chem Biol 2017[Feb]; 36 (ä): 70-76 PMID28213207 show ga Enzymatic transformations of primary, canonical metabolites generate active biomolecules that regulate important cellular and physiological processes. Roles include regulation of histone demethylation in epigenetics, inflammation in tissue injury, insulin sensitivity, cancer cell invasion, stem cell pluripotency status, inhibition of nitric oxide signaling and others. Such modified compounds, defined as epimetabolites, have functions distinct from classic hormones as well as removed from generic anabolism and catabolism. Epimetabolites are discovered by untargeted metabolomics using liquid- or gas chromatography-high resolution mass spectrometry and structurally annotated by in-silico fragmentation prediction tools. Their specific biological functions are subsequently investigated by targeted metabolomics methods. |*Metabolome [MESH] |Chromatography/*methods [MESH] |Humans [MESH] |Mass Spectrometry/*methods [MESH] |Metabolomics/*methods [MESH] |Molecular Structure [MESH]Epimetabolites: discovering metabolism beyond building and burning (epmc).pdf DeepDyve Pubget Overpricing