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2017 ; 4
(1
): 15-20
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Epigenetic memory and cell fate reprogramming in plants
#MMPMID28316791
Birnbaum KD
; Roudier F
Regeneration (Oxf)
2017[Feb]; 4
(1
): 15-20
PMID28316791
show ga
Plants have a high intrinsic capacity to regenerate from adult tissues, with the
ability to reprogram adult cell fates. In contrast, epigenetic mechanisms have
the potential to stabilize cell identity and maintain tissue organization. The
question is whether epigenetic memory creates a barrier to reprogramming that
needs to be erased or circumvented in plant regeneration. Early evidence suggests
that, while chromatin dynamics impact gene expression in the meristem, a lasting
constraint on cell fate is not established until late stages of plant cell
differentiation. It is not yet clear whether the plasticity of plant cells arises
from the ability of cells to erase identity memory or to deploy cells that may
exhibit cellular specialization but still lack an epigenetic restriction on cell
fate alteration.