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10.1007/s13311-014-0302-1 http://scihub22266oqcxt.onion/10.1007/s13311-014-0302-1 C4391378!4391378 !25261112     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25261112 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25261112 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Neurotherapeutics 2014 ; 11 (4 ): 708-20 Nephropedia Template TP {{tp|p=25261112 |t=2014. Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases |pdf=|usr=}}{{25261112 }} gab.com Text Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases JO: Neurotherapeutics http://www.kidney.de/pget.php?&tw=1&pmid=25261112 #FOAvip There have been considerable advances in uncovering the complex genetic mechanisms that underlie nervous system disease pathogenesis, particularly with the advent of exome and whole genome sequencing techniques. The emerging field of epigenetics is also providing further insights into these mechanisms. Here, we discuss our understanding of the interplay that exists between genetic and epigenetic mechanisms in these disorders, highlighting the nascent field of epigenetic epidemiology-which focuses on analyzing relationships between the epigenome and environmental exposures, development and aging, other health-related phenotypes, and disease states-and next-generation research tools (i.e., those leveraging synthetic and chemical biology and optogenetics) for examining precisely how epigenetic modifications at specific genomic sites affect disease processes. Twit Text FOAVip Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases ????Neurotherapeutics http://www.kidney.de/pget.php?&tw=1&pmid=25261112 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25261112 #FOAvip English Wikipedia <ref>{{Cite pmid|25261112 }}</ref> Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases #MMPMID25261112 Qureshi IA ; Mehler MF Neurotherapeutics 2014[Oct]; 11 (4 ): 708-20 PMID25261112 show ga There have been considerable advances in uncovering the complex genetic mechanisms that underlie nervous system disease pathogenesis, particularly with the advent of exome and whole genome sequencing techniques. The emerging field of epigenetics is also providing further insights into these mechanisms. Here, we discuss our understanding of the interplay that exists between genetic and epigenetic mechanisms in these disorders, highlighting the nascent field of epigenetic epidemiology-which focuses on analyzing relationships between the epigenome and environmental exposures, development and aging, other health-related phenotypes, and disease states-and next-generation research tools (i.e., those leveraging synthetic and chemical biology and optogenetics) for examining precisely how epigenetic modifications at specific genomic sites affect disease processes. |*Epigenesis, Genetic [MESH] |Epigenomics [MESH] |Humans [MESH]Epigenetic mechanisms underlying the pathogenesis of neurogenetic dise(epmc).pdf DeepDyve Pubget Overpricing