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10.1007/s12026-014-8536-x http://scihub22266oqcxt.onion/10.1007/s12026-014-8536-x C5106292!5106292 !24838146     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24838146 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24838146 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Immunol+Res 2014 ; 59 (1-3 ): 129-41 Nephropedia Template TP {{tp|p=24838146 |t=2014. Eosinophils and mast cells in leishmaniasis |pdf=|usr=}}{{24838146 }} gab.com Text Eosinophils and mast cells in leishmaniasis JO: Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=24838146 #FOAvip Leishmania spp. are parasitic protozoa endemic in tropical and subtropical regions and the causative agent of leishmaniasis, a collection of syndromes whose clinical manifestations vary according to host and pathogen factors. Leishmania spp. are inoculated into the mammalian host by the bite of an infected sand fly, whereupon they are taken up by phagocytosis, convert into the replicative amastigote stage within macrophages, reproduce, spread to new macrophages and cause disease manifestations. A curative response against leishmaniasis depends in the classical activation of macrophages and the IL-12-dependent onset of an adaptive type 1 response characterized by the production of IFN-?. Emerging evidence suggests that neutrophils, dendritic cells and other immune cells can serve as either temporary or stable hosts for Leishmania spp. Furthermore, it is becoming apparent that the initial interactions of the parasite with resident or early recruited immune cells can shape both the macrophage response and the type of adaptive immune response being induced. In this review, we compile a growing number of studies demonstrating how the earliest interactions of Leishmania spp. with eosinophils and mast cells influence the macrophage response to infection and the development of the adaptive immune response, hence, determining the ultimate outcome of infection. Twit Text FOAVip Eosinophils and mast cells in leishmaniasis ????Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=24838146 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24838146 #FOAvip English Wikipedia <ref>{{Cite pmid|24838146 }}</ref> Eosinophils and mast cells in leishmaniasis #MMPMID24838146 Rodríguez NE ; Wilson ME Immunol Res 2014[Aug]; 59 (1-3 ): 129-41 PMID24838146 show ga Leishmania spp. are parasitic protozoa endemic in tropical and subtropical regions and the causative agent of leishmaniasis, a collection of syndromes whose clinical manifestations vary according to host and pathogen factors. Leishmania spp. are inoculated into the mammalian host by the bite of an infected sand fly, whereupon they are taken up by phagocytosis, convert into the replicative amastigote stage within macrophages, reproduce, spread to new macrophages and cause disease manifestations. A curative response against leishmaniasis depends in the classical activation of macrophages and the IL-12-dependent onset of an adaptive type 1 response characterized by the production of IFN-?. Emerging evidence suggests that neutrophils, dendritic cells and other immune cells can serve as either temporary or stable hosts for Leishmania spp. Furthermore, it is becoming apparent that the initial interactions of the parasite with resident or early recruited immune cells can shape both the macrophage response and the type of adaptive immune response being induced. In this review, we compile a growing number of studies demonstrating how the earliest interactions of Leishmania spp. with eosinophils and mast cells influence the macrophage response to infection and the development of the adaptive immune response, hence, determining the ultimate outcome of infection. |Animals [MESH] |Eosinophils/*immunology/pathology [MESH] |Humans [MESH] |Interferon-gamma/immunology [MESH] |Interleukin-12/immunology [MESH] |Leishmania/*immunology [MESH] |Leishmaniasis/*immunology/pathology [MESH] |Mast Cells/*immunology/pathology [MESH] |Phagocytosis/immunology [MESH]Eosinophils and mast cells in leishmaniasis (epmc).pdf DeepDyve Pubget Overpricing