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2014 ; 43
(2
): 317-27
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Eosinophilic gastroenteritis and related eosinophilic disorders
#MMPMID24813518
Prussin C
Gastroenterol Clin North Am
2014[Jun]; 43
(2
): 317-27
PMID24813518
show ga
Eosinophilic gastroenteritis (EGE) represents one member within the spectrum of
diseases collectively referred to as eosinophilic gastrointestinal disorders,
which includes eosinophilic esophagitis (EoE), gastritis, enteritis, and colitis.
EGE is less common than EoE and involves a different site of disease but
otherwise shares many common features with EoE. The clinical manifestations of
EGE are protean and can vary from nausea and vomiting to protein-losing
enteropathy or even bowel obstruction requiring surgery. Although systemic
corticosteroids are an effective treatment for EGE, their use results in
substantial corticosteroid toxicity. Accordingly, there is a great need for
improved therapies for these patients.