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2014 ; 43
(2
): 185-99
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Eosinophilic esophagitis: historical perspective on an evolving disease
#MMPMID24813509
Attwood SE
; Furuta GT
Gastroenterol Clin North Am
2014[Jun]; 43
(2
): 185-99
PMID24813509
show ga
Initial case series describing children and adults with symptoms related to
esophageal dysfunction and dense esophageal eosinophilia lead to recognition of a
"new" disease, eosinophilic esophagitis (EoE). Clinical, basic, and translational
studies have provided a deeper understanding of this somewhat enigmatic disease
that mechanistically is defined as an antigen-driven condition limited to the
esophagus. This article summarizes many of the key historical features of EoE and
provides a glimpse of potential future developments.