Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24480293
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Curr+Opin+Genet+Dev
2014 ; 25
(ä): 38-42
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Enhancer RNAs: the new molecules of transcription
#MMPMID24480293
Lai F
; Shiekhattar R
Curr Opin Genet Dev
2014[Apr]; 25
(ä): 38-42
PMID24480293
show ga
In the past few years, technological advances in nucleotide sequencing have
culminated in a greater understanding of the complexity of the human
transcriptome. Notably, the discovery that distal regulatory elements known as
enhancers are transcribed and such enhancer-derived transcripts (eRNAs) serve a
critical function in transcriptional activation has added a new dimension to
transcriptional regulation. Here we review recent insights into the
tissue-specific and temporal-specific gene regulation brought about by the
discovery of eRNAs.