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2015 ; 21
(47
): 13212-24
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Endoscopic ultrasound elastography: Current status and future perspectives
#MMPMID26715804
Cui XW
; Chang JM
; Kan QC
; Chiorean L
; Ignee A
; Dietrich CF
World J Gastroenterol
2015[Dec]; 21
(47
): 13212-24
PMID26715804
show ga
Elastography is a new ultrasound modality that provides images and measurements
related to tissue stiffness. Endoscopic ultrasound (EUS) has played an important
role in the diagnosis and management of numerous abdominal and mediastinal
diseases. Elastography by means of EUS examination can assess the elasticity of
tumors in the proximity of the digestive tract that are hard to reach with
conventional transcutaneous ultrasound probes, such as pancreatic masses and
mediastinal or abdominal lymph nodes, thus improving the diagnostic yield of the
procedure. Results from previous studies have promised benefits for EUS
elastography in the differential diagnosis of lymph nodes, as well as for
assessing masses with pancreatic or gastrointestinal (GI) tract locations. It is
important to mention that EUS elastography is not considered a modality that can
replace biopsy. However, it may be a useful adjunct, improving the accuracy of
EUS-fine needle aspiration biopsy (EUS-FNAB) by selecting the most suspicious
area to be targeted. Even more, it may be useful for guiding further clinical
management when EUS-FNAB is negative or inconclusive. In the present paper we
will discuss the current knowledge of EUS elastography, including the technical
aspects, along with its applications in the differential diagnosis between benign
and malignant solid pancreatic masses and lymph nodes, as well as its aid in the
differentiation between normal pancreatic tissues and chronic pancreatitis.
Moreover, the emergent indication and future perspectives are summarized, such as
the benefit of EUS elastography in EUS-guided fine needle aspiration biopsy, and
its uses for characterization of lesions in liver, biliary tract, adrenal glands
and GI tract.
|*Endosonography
[MESH]
|Diagnosis, Differential
[MESH]
|Elasticity
[MESH]
|Elasticity Imaging Techniques/*methods
[MESH]
|Endoscopic Ultrasound-Guided Fine Needle Aspiration
[MESH]