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10.1038/nrm3440

http://scihub22266oqcxt.onion/10.1038/nrm3440
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C5111635!5111635 !22992592
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suck abstract from ncbi


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pmid22992592
      Nat+Rev+Mol+Cell+Biol 2012 ; 13 (10 ): 607-25
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  • Endoplasmic reticulum-mitochondria contacts: function of the junction #MMPMID22992592
  • Rowland AA ; Voeltz GK
  • Nat Rev Mol Cell Biol 2012[Oct]; 13 (10 ): 607-25 PMID22992592 show ga
  • The most well-characterized organelle contact sites are those between the endoplasmic reticulum (ER) and mitochondria. Increased understanding is being gained of how ER-mitochondria contact sites are organized and which factors converge at this interface, some of which may provide a tethering function. The role of the ER-mitochondria junction in coordinating the functions of these two organelles is also becoming clearer, and it has been shown to be involved in the regulation of lipid synthesis, Ca(2+) signalling and the control of mitochondrial biogenesis and intracellular trafficking.
  • |Animals [MESH]
  • |Calcium Signaling [MESH]
  • |Endoplasmic Reticulum/*metabolism/*ultrastructure [MESH]
  • |Lipids/biosynthesis [MESH]
  • |Mitochondria/*metabolism/*ultrastructure [MESH]
  • |Mitochondrial Membranes/metabolism/ultrastructure [MESH]
  • |Mitochondrial Turnover [MESH]
  • |Protein Transport [MESH]


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