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2017 ; 31
(2
): 106-108
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Endogenous Brucella endophthalmitis: A case report
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Oray M
; Cebeci Z
; Kir N
; Turgut Ozturk B
; Oksuz L
; Tugal-Tutkun I
Saudi J Ophthalmol
2017[Apr]; 31
(2
): 106-108
PMID28559723
show ga
Brucellosis may be associated with a wide range of ophthalmic manifestations
including endophthalmitis, which is a sight-threatening condition that needs to
be rapidly recognized and treated to avoid permanent visual loss. A 26-year-old
female with a 6-month history of vision loss in the left eye was treated with
high dose systemic corticosteroids and azathioprine with an initial misdiagnosis
elsewhere. A dense vitreous haze with opacities at the posterior hyaloid and a
wide area of retinochoroiditis led to the diagnosis of endogenous endophthalmitis
at presentation to us. The vitreous sample and blood cultures demonstrated growth
of Brucella melitensis. She received 6 months of systemic antibiotherapy, which
resulted in resolution of inflammation; however, visual acuity remained poor due
to irreversible damage. Infectious etiology, including brucellosis in endemic
countries, has to be considered in the differential diagnosis before
administering immunomodulatory therapy in patients with panuveitis of unknown
origin.
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