Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26494962
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 World+J+Gastroenterol
2015 ; 21
(39
): 11053-76
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Endocrine causes of nonalcoholic fatty liver disease
#MMPMID26494962
Marino L
; Jornayvaz FR
World J Gastroenterol
2015[Oct]; 21
(39
): 11053-76
PMID26494962
show ga
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic
liver disease in the industrialized world. The prevalence of NAFLD is increasing,
becoming a substantial public health burden. NAFLD includes a broad spectrum of
disorders, from simple conditions such as steatosis to severe manifestations such
as fibrosis and cirrhosis. The relationship of NAFLD with metabolic alterations
such as type 2 diabetes is well described and related to insulin resistance, with
NAFLD being recognized as the hepatic manifestation of metabolic syndrome.
However, NAFLD may also coincide with endocrine diseases such as polycystic ovary
syndrome, hypothyroidism, growth hormone deficiency or hypercortisolism. It is
therefore essential to remember, when discovering altered liver enzymes or
hepatic steatosis on radiological exams, that endocrine diseases can cause NAFLD.
Indeed, the overall prognosis of NAFLD may be modified by treatment of the
underlying endocrine pathology. In this review, we will discuss endocrine
diseases that can cause NALFD. Underlying pathophysiological mechanisms will be
presented and specific treatments will be reviewed.
|Animals
[MESH]
|Endocrine System
Diseases/*complications/diagnosis/metabolism/physiopathology/therapy
[MESH]
free
free
free
