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Encéphalopathie pancréatique: à propos de deux cas
#MMPMID28292109
Doghmi N
; Benakrout A
; Meskine A
; Bensghir M
; Baite A
; Haimeur C
Pan Afr Med J
2016[]; 25
(?): 147
PMID28292109
show ga
Pancreatic encephalopathy (PE) is a rare complication of acute pancreatitis. Our
study reports 2 cases of patients with pancreatic encephalopathy, hospitalized
and treated in the Intensive Care Unit of the Military Hospital of Instruction
Mohammed V, Rabat. Patient age ranged between 43 and 54 years, our 2 cases
involved a woman and a man. The pathophysiologic process of EP is still not well
understood, many assumptions have been described in the literature; some authors
have suggested that lipase and phospholipase A2 are involved in the pathological
process of PE. Other factors including infections, fluid and electrolyte
disturbances, hypoxemia and perturbations in blood glucose can be triggers. The
diagnosis of pancreatic encephalopathy is easy to establish, clinical symptoms
usually include confusion, amazement and psychomotor agitation, sometimes
associated with neurological damages such as convulsions, headache, transient
hemiparesis, dysarthria, difficulties in verbal expression and amnesia.
Paraclinical tests, including brain MRI and electroencephalogram allow a
definitive diagnosis. Treatment is primarily symptomatic aiming to fight against
factors favoring the onset of neurologic signs using resuscitative measures based
on severity of the situation. The prognosis depends on the severity of acute
pancreatitis and its complications. In our study data are broadly comparable to
those currently published by the majority of authors.
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