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10.1186/s12916-017-0840-6 http://scihub22266oqcxt.onion/10.1186/s12916-017-0840-6 C5382440!5382440 !28381299     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28381299 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28381299 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMC+Med 2017 ; 15 (1 ): 75 Nephropedia Template TP {{tp|p=28381299 |t=2017. Emerging concepts in liquid biopsies |pdf=|usr=}}{{28381299 }} gab.com Text Emerging concepts in liquid biopsies JO: BMC Med http://www.kidney.de/pget.php?&tw=1&pmid=28381299 #FOAvip Characterizing and monitoring tumor genomes with blood samples could achieve significant improvements in precision medicine. As tumors shed parts of themselves into the circulation, analyses of circulating tumor cells, circulating tumor DNA, and tumor-derived exosomes, often referred to as "liquid biopsies", may enable tumor genome characterization by minimally invasive means. Indeed, multiple studies have described how molecular information about parent tumors can be extracted from these components. Here, we briefly summarize current technologies and then elaborate on emerging novel concepts that may further propel the field. We address normal and detectable mutation levels in the context of our current knowledge regarding the gradual accumulation of mutations during aging and in light of technological limitations. Finally, we discuss whether liquid biopsies are ready to be used in routine clinical practice. Twit Text FOAVip Emerging concepts in liquid biopsies ????BMC Med http://www.kidney.de/pget.php?&tw=1&pmid=28381299 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28381299 #FOAvip English Wikipedia <ref>{{Cite pmid|28381299 }}</ref> Emerging concepts in liquid biopsies #MMPMID28381299 Perakis S ; Speicher MR BMC Med 2017[Apr]; 15 (1 ): 75 PMID28381299 show ga Characterizing and monitoring tumor genomes with blood samples could achieve significant improvements in precision medicine. As tumors shed parts of themselves into the circulation, analyses of circulating tumor cells, circulating tumor DNA, and tumor-derived exosomes, often referred to as "liquid biopsies", may enable tumor genome characterization by minimally invasive means. Indeed, multiple studies have described how molecular information about parent tumors can be extracted from these components. Here, we briefly summarize current technologies and then elaborate on emerging novel concepts that may further propel the field. We address normal and detectable mutation levels in the context of our current knowledge regarding the gradual accumulation of mutations during aging and in light of technological limitations. Finally, we discuss whether liquid biopsies are ready to be used in routine clinical practice. |Animals [MESH] |Biopsy/*methods [MESH] |DNA, Neoplasm/blood/*genetics [MESH] |Humans [MESH] |Neoplastic Cells, Circulating/*pathology [MESH]Emerging concepts in liquid biopsies (epmc).pdf DeepDyve Pubget Overpricing