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http://scihub22266oqcxt.onion/ C5168830!5168830 !28018143     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28018143 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Yale+J+Biol+Med 2016 ; 89 (4 ): 527-537 Nephropedia Template TP {{tp|p=28018143 |t=2016. Emerging Functions of Circular RNAs |pdf=|usr=}}{{28018143 }} gab.com Text Emerging Functions of Circular RNAs JO: Yale J Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=28018143 #FOAvip Many thousands of Circular RNAs (circRNAs) have recently been identified in metazoan genomes by transcriptome-wide sequencing. Most circRNAs are generated by back-splicing events from exons of protein-coding genes. A great deal of progress has recently been made in understanding the genome-wide expression patterns, biogenesis, and regulation of circRNAs. To date, however, few functions of circRNAs have been identified. CircRNAs are preferentially expressed in neural tissues and some are found at synapses, suggesting possible functions in the nervous system. Several circRNAs have been shown to function as microRNA "sponges" to counteract microRNA mediated repression of mRNA. New functions for circRNAs are arising, including protein sequestration, transcriptional regulation, and potential functions in cancer. Here, we highlight the recent progress made in understanding the biogenesis and regulation of circRNAs, discuss newly uncovered circRNA functions, and explain the methodological approaches that could reveal more exciting and unexpected roles for these RNAs. Twit Text FOAVip Emerging Functions of Circular RNAs ????Yale J Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=28018143 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28018143 #FOAvip English Wikipedia <ref>{{Cite pmid|28018143 }}</ref> Emerging Functions of Circular RNAs #MMPMID28018143 Cortés-López M ; Miura P Yale J Biol Med 2016[Dec]; 89 (4 ): 527-537 PMID28018143 show ga Many thousands of Circular RNAs (circRNAs) have recently been identified in metazoan genomes by transcriptome-wide sequencing. Most circRNAs are generated by back-splicing events from exons of protein-coding genes. A great deal of progress has recently been made in understanding the genome-wide expression patterns, biogenesis, and regulation of circRNAs. To date, however, few functions of circRNAs have been identified. CircRNAs are preferentially expressed in neural tissues and some are found at synapses, suggesting possible functions in the nervous system. Several circRNAs have been shown to function as microRNA "sponges" to counteract microRNA mediated repression of mRNA. New functions for circRNAs are arising, including protein sequestration, transcriptional regulation, and potential functions in cancer. Here, we highlight the recent progress made in understanding the biogenesis and regulation of circRNAs, discuss newly uncovered circRNA functions, and explain the methodological approaches that could reveal more exciting and unexpected roles for these RNAs. |Alternative Splicing/genetics [MESH] |Animals [MESH] |Exons/genetics [MESH] |Gene Expression Regulation/genetics [MESH] |Humans [MESH] |MicroRNAs/genetics [MESH] |RNA, Circular [MESH] |RNA, Untranslated/genetics [MESH]Emerging Functions of Circular RNAs (epmc).pdf DeepDyve Pubget Overpricing