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10.1101/cshperspect.a015784

http://scihub22266oqcxt.onion/10.1101/cshperspect.a015784
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C4484974!4484974 !26134313
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suck abstract from ncbi


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pmid26134313
      Cold+Spring+Harb+Perspect+Biol 2015 ; 7 (7 ): a015784
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  • Emergent Properties of the Metaphase Spindle #MMPMID26134313
  • Reber S ; Hyman AA
  • Cold Spring Harb Perspect Biol 2015[Jul]; 7 (7 ): a015784 PMID26134313 show ga
  • A metaphase spindle is a complex structure consisting of microtubules and a myriad of different proteins that modulate microtubule dynamics together with chromatin and kinetochores. A decade ago, a full description of spindle formation and function seemed a lofty goal. Here, we describe how work in the last 10 years combining cataloging of spindle components, the characterization of their biochemical activities using single-molecule techniques, and theory have advanced our knowledge. Taken together, these advances suggest that a full understanding of spindle assembly and function may soon be possible.
  • |*Metaphase [MESH]
  • |*Models, Biological [MESH]
  • |Animals [MESH]
  • |Microtubule-Associated Proteins/chemistry/metabolism/physiology [MESH]
  • |Microtubules/chemistry/metabolism/physiology [MESH]
  • |Spindle Apparatus/chemistry/metabolism/*physiology [MESH]


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