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10.15252/embj.201694227

http://scihub22266oqcxt.onion/10.15252/embj.201694227
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C5207320!5207320 !27006277
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suck abstract from ncbi


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pmid27006277
      EMBO+J 2016 ; 35 (9 ): 907-8
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  • Elucidating the DDK-dependent step in replication initiation #MMPMID27006277
  • Araki H
  • EMBO J 2016[May]; 35 (9 ): 907-8 PMID27006277 show ga
  • By phosphorylating specific replication factors, cell cycle kinases ensure that eukaryotic DNA replication is initiated once and only once per mitotic cell division. New work in The EMBO Journal now reveals how DDK?mediated phosphorylation of Mcm2?7 helicase subunits is read out by Sld3, which provides further integration with CDK phosphorylation.
  • |*DNA Replication [MESH]
  • |Cell Cycle Proteins/*genetics [MESH]
  • |Humans [MESH]
  • |Protein Serine-Threonine Kinases/genetics [MESH]


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