Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25365680
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Anal+Chem
2014 ; 86
(22
): 11174-80
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Electroosmotic flow in nanofluidic channels
#MMPMID25365680
Haywood DG
; Harms ZD
; Jacobson SC
Anal Chem
2014[Nov]; 86
(22
): 11174-80
PMID25365680
show ga
We report the measurement of electroosmotic mobilities in nanofluidic channels
with rectangular cross sections and compare our results with theory. Nanofluidic
channels were milled directly into borosilicate glass between two closely spaced
microchannels with a focused ion beam instrument, and the nanochannels had
half-depths (h) of 27, 54, and 108 nm and the same half-width of 265 nm. We
measured electroosmotic mobilities in NaCl solutions from 0.1 to 500 mM that have
Debye lengths (?(-1)) from 30 to 0.4 nm, respectively. The experimental
electroosmotic mobilities compare quantitatively to mobilities calculated from a
nonlinear solution of the Poisson-Boltzmann equation for channels with a
parallel-plate geometry. For the calculations, ?-potentials measured in a
microchannel with a half-depth of 2.5 ?m are used and range from -6 to -73 mV for
500 to 0.1 mM NaCl, respectively. For ?h > 50, the Smoluchowski equation
accurately predicts electroosmotic mobilities in the nanochannels. However, for
?h < 10, the electrical double layer extends into the nanochannels, and due to
confinement within the channels, the average electroosmotic mobilities decrease.
At ?h ? 4, the electroosmotic mobilities in the 27, 54, and 108 nm channels
exhibit maxima, and at 0.1 mM NaCl, the electroosmotic mobility in the 27 nm
channel (?h = 1) is 5-fold lower than the electroosmotic mobility in the 2.5 ?m
channel (?h = 100).
free
free
free
