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2015 ; 5
(ä): 11242
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Electronic polymers in lipid membranes
#MMPMID26059023
Johansson PK
; Jullesson D
; Elfwing A
; Liin SI
; Musumeci C
; Zeglio E
; Elinder F
; Solin N
; Inganäs O
Sci Rep
2015[Jun]; 5
(ä): 11242
PMID26059023
show ga
Electrical interfaces between biological cells and man-made electrical devices
exist in many forms, but it remains a challenge to bridge the different
mechanical and chemical environments of electronic conductors (metals,
semiconductors) and biosystems. Here we demonstrate soft electrical interfaces,
by integrating the metallic polymer PEDOT-S into lipid membranes. By preparing
complexes between alkyl-ammonium salts and PEDOT-S we were able to integrate
PEDOT-S into both liposomes and in lipid bilayers on solid surfaces. This is a
step towards efficient electronic conduction within lipid membranes. We also
demonstrate that the PEDOT-S@alkyl-ammonium:lipid hybrid structures created in
this work affect ion channels in the membrane of Xenopus oocytes, which shows the
possibility to access and control cell membrane structures with conductive
polyelectrolytes.