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10.2147/IDR.S69596

http://scihub22266oqcxt.onion/10.2147/IDR.S69596
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C4459619!4459619 !26082652
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suck abstract from ncbi


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pmid26082652
      Infect+Drug+Resist 2015 ; 8 (ä): 163-72
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  • Efinaconazole in the treatment of onychomycosis #MMPMID26082652
  • Lipner SR ; Scher RK
  • Infect Drug Resist 2015[]; 8 (ä): 163-72 PMID26082652 show ga
  • Efinaconazole 10% topical solution is a new triazole recently approved for the treatment of onychomycosis. It inhibits fungal lanosterol 14?-demethylase in the ergosterol biosynthesis pathway, has potent antifungal activity against dermatophytes, as well as activity against Candida spp. and non-dermatophyte molds, and showed promising results in clinical trials. This review summarizes the mechanism of action, in vitro and in vivo data, clinical trials, safety, and quality-of-life data of efinaconazole as it applies to the treatment of onychomycosis.
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