Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26082652
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Infect+Drug+Resist
2015 ; 8
(ä): 163-72
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Efinaconazole in the treatment of onychomycosis
#MMPMID26082652
Lipner SR
; Scher RK
Infect Drug Resist
2015[]; 8
(ä): 163-72
PMID26082652
show ga
Efinaconazole 10% topical solution is a new triazole recently approved for the
treatment of onychomycosis. It inhibits fungal lanosterol 14?-demethylase in the
ergosterol biosynthesis pathway, has potent antifungal activity against
dermatophytes, as well as activity against Candida spp. and non-dermatophyte
molds, and showed promising results in clinical trials. This review summarizes
the mechanism of action, in vitro and in vivo data, clinical trials, safety, and
quality-of-life data of efinaconazole as it applies to the treatment of
onychomycosis.